13th International Conference on Genomics and Molecular Biology
May 25-26, 2020 Rome, Italy
Beta thalassemia or Cooley’s anemia is caused by mutations in the beta chain of the hemoglobin molecule. There is one beta chain gene on each 11th chromosome, for a total of two. How these genes are altered determines the specific type of beta thalassemia in a child. This form of thalassemia is usually so severe that it requires regular blood transfusions.
The symptoms of Cooley’s anemia generally appear before a child’s second birthday. The severe anemia related to this condition can be life-threatening. Children born with Cooley’s anemia are normal at birth, but develop severe anemia during the first year of life.
Cooley’s anemia effects approximately 1 in 272,000 or 0.00% or 1,000 people. In USA 38 from 10,348,276 people were affected from Cooley’s anemia.