Microscopic colitis: Microscopic colitis is a type of inflammation of the colon, or large intestine, that can cause watery diarrhea and cramping. While it can be painful and unpleasant, it's much less severe than other types of inflammatory bowel disease. Microscopic colitis is an inflammation of the large intestine (colon) that causes persistent watery diarrhea. The disorder gets its name from the fact that it's necessary to examine colon tissue under a microscope to identify it. The annual number of reported cases is about 10 to 15.7 cases per 100,000.
Tests and diagnosis: A complete medical history and physical examination can help determine whether other conditions may be contributing to your diarrhea, including: Celiac disease, Autoimmune disorders, such as rheumatoid arthritis. Colonoscopy or flexible sigmoidoscopy with biopsy to help rule out other intestinal disorders. Both tests use a long, thin tube with a camera on the end to examine the inside of your colon. The colons of people with microscopic colitis appear normal. A biopsy can be obtained during colonoscopy or flexible sigmoidoscopy and analyzed for signs of microscopic colitis.
Treatment for Microscopic Colitis: Avoid food or drinks that could make symptoms worse, like caffeine, dairy, and fatty foods, Take fiber supplements, Stop taking medication that could trigger symptoms, Over-the-counter drugs to stop diarrhea, such as Imodium and Pepto-Bismol, Prescription drugs to reduce swelling, such as mesalamine (Asacol, Colazal, Pentasa, and others), sulfasalazine (Azulfidine), or steroids.