Polyps are an end result of varying disease processes in the nasal cavities. The most commonly discussed polyps are benign semitransparent nasal lesions (see the images below) that arise from the mucosa of the nasal cavity or from one or more of the paranasal sinuses, often at the outflow tract of the sinuses. Although CF has a varied phenotypic presentation, pulmonary and sinonasal involvement occurs in 90-100% of CF patients. Approximately 80% of patients with CF have nasal obstruction, 25% have anosmia, and more than 50% complain of rhinorrhea and headache. The prevalence of nasal polyposis in patients with CF appears to depend on age, increasing during adolescence and ranging from 6% to 48%.
Antihistamines, decongestants, and cromolyn sodium provide little benefit. Immunotherapy may be useful to treat allergic rhinitis but, when used alone, does not usually resolve existing polyps. Administer antibiotics for bacterial superinfections. Although much work has been done on chronic rhinosinusitis and nasal polyps there are many questions still unanswered. A prospective population study of a group of age- and sex-matched controlled atopic and non-atopic individuals to consider the incidence of all upper respiratory tract symptoms including acute and chronic rhinosinusitis over a 5 year period.