Odontogenic tumors (OTs) are lesions that develop exclusively on maxillary bones, and form a heterogeneous group. Odontogenic tumors (OTs) develop exclusively on gnathic bones through the proliferation of odontogenic tissues (epithelial, mesenchymal or both). According to their origins, they are divided into epithelial, ectomesenchymal, and mesenchymal. The lesions were most prevalent in the age group between 21 and 30 years. Among the radiopaque lesions two cases were odontomas (67%), and one case was cementoblastoma (33%). Nine cases (12%) had no information concerning radiographic characteristics: seven were odontoma (78%), one case was myxoma (11%), and one case was central odontogenic fibroma (COF, 11%) in Brazil. Recent Epidemologic studies revealed that the prevalence of Odontogenic Tumors in Brazil was 0.5%.
Microscopically, squamous odontogenic tumor appears as islands of bland squamous epithelium (no cellular atypia or mitotic figures) without an inflammatory infiltrate. Peripheral palisades are not seen. The epithelial islands are occasionally closely associated with bone spicules. There is superficial resemblance to ameloblastoma (acanthomatous type) and well-differentiated squamous cell carcinoma. Researches are focusing on Multicenter Retrospective Cohort Study on Pediatric Oral Lesions, Differential expression of TLR3 and TLR4 in keratocystic odontogenic tumor (KCOT): A comparative immunohistochemical study in primary, recurrent, and nevoid basal cell carcinoma syndrome (NBCCS)-associated lesions.