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Peripheral Nerve Tumors

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  • Peripheral Nerve Tumors

    Pathophysiology
    Nerve tumors can form in the peripheral nerve network anywhere in the body. These tumors often affect the function of the nerve, causing pain and disability. A large majority of peripheral nerve tumors are benign. Some are caused by neurofibromatosis, or schwannomatosis. Malignant Peripheral Nerve Sheath Tumors are very aggressive tumors and should be managed by a multi-disciplinary team.

  • Peripheral Nerve Tumors

    Disease statistics
    The average 5-year brain tumor survival rate for 22 European countries when including follow-up date through 1998 was 18%. 2012 estimated incidence rates for different cancers in males: lung-66.3, melanoma of skin-13.2, cervix-0, prostate-110.8. In females: lung-26.1, melanoma of skin-11.0, female breast cancer-108.8, cervix-11.3, prostate-0.

  • Peripheral Nerve Tumors

    Disease treatment
    There are several factors in deciding to surgically remove these tumors. Some, like schwannomas are slow-growing and can be watched using imaging studies over time. Others, like malignant nerve sheath tumors need to be removed immediately, as they are very aggressive.

  • Peripheral Nerve Tumors

    Major research
    Current research in on understanding the molecular mechanisms that normally act to arrest tumor growth as well as those that promote nerve tumor, currently comparing and contrasting the molecular profile of growing and non-growing tumors in patients with NF1.

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