Sclerosing mesenteritis occurs when the tissue (mesentery) that holds the small intestines in place becomes inflamed and forms scar tissue. Sclerosing mesenteritis is rare, and it's not clear what causes it.
Sclerosing mesenteritis is characterized by chronic inflammation, fibrosis and fat necrosis, and is thought to originate from the small bowel mesentery.Sclerosing mesenteritis is chronic inflammation and fibrosis of the mesentery of unknown etiology. Sclerosing mesenteritis, inflammatory pseudotumor, retroperitoneal fibrosis and IgG-4 related disease are rare inflammatory conditions that may present as a pelvic mass and mimic malignancy or infection.
sclerosing mesenteritis is asymptomatic, gastrointestinal symptoms such as abdominal pain, nausea/vomiting, bloating, loss of appetite, weight loss and diarrhea or constipation, Occasionally, intermittent partial bowel obstruction is encountered. Non-gastrointestinal symptoms include fatigue, weight loss, night sweats and fever.Sclerosing mesenteritis occurs when the tissue mesentery that holds the small intestines in place becomes inflamed and forms scar tissue.Sclerosing mesenteritis can cause abdominal pain, bloating and diarrhea. In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through your digestive tract. Surgery may be necessary in this situation.
The best treatment for sclerosing mesenteritis remains unclear. Asymptomatic or mild clinical forms may sometimes be left untreated with spontaneous recovery . Surgical resection is required for patients with intestinal obstruction and perforation, and immunosuppressive therapy with corticosteroids, thalidomide, and other drugs has been recommended by some authors.