Typhoid fever is a systemic disease caused by the human specific Gram negative pathogen named Salmonella enterica serovar Typhi (S. Typhi). The extra-intestinal infections caused by Salmonella are very fatal. The incidence of typhoid fever remains very high in impoverished areas and the emergence of multidrug resistance has made the situation worse. Typhoid fever incidence is increasing day by day in brazil. The mortality rates due to Typhoid fever is 11.4%.
Symptoms that occur include Abdominal tenderness, Agitation, Bloody stools, Chills, Confusion, Difficulty paying attention (attention deficit), Delirium, Fluctuating mood, Hallucinations, Nosebleeds, Severe fatigue, lethargic feeling Weakness. Fluids and electrolytes may be given by IV (into a vein). Antibiotics are given to kill the bacteria. There are increasing rates of antibiotic resistance throughout the world, so your health care provider will check current recommendations before choosing an antibiotic. Researches going on Comparative genomics study for identification of putative drug targets in Salmonella typhi Type 2, Clinical Outcome of a Portosplenomesenteric Venous Thrombosis in Necrotizing Acute Pancreatitis with Protein C and S Deficiency Treated by Anticoagulation Therapy Alone.