Typhus is a disease caused by bacteria (mainly Rickettsia typhi or R. prowazekii). There are two major types of typhus: endemic (or murine typhus) and epidemic typhus. The disease occurs after bacteria (Rickettsia spp.) are transferred to humans usually by vectors such as fleas or lice.Rickettsiae microorganisms appear to exert their pathologic effects by adhering to and then invading the endothelial lining of the vasculature within the various organs affected. The adhesins appear to be outer membrane proteins that allow the rickettsia to be phagocytosed into the host cell.
In the Brazil, about 5,362 cases of Typhus fever are reported in each year. Almost 14% of the Brazil population is suffering with Typhus fever, a disease caused by bacteria called Rickettsia typhi or bacteria called Rickettsia felis.Early treatment with antibiotics is effective and relapses are uncommon. Treatment is sometimes begun before laboratory confirmation, particularly when the symptoms are severe. esidual insecticide treatment of the clothing and hair is recommended for people who may have been exposed to infected lice.