Acanthosis nigricans is a skin condition characterized by areas of dark, velvety discoloration in body folds and creases. The affected skin can become thickened. Most often, acanthosis nigricans affects your armpits, groin and neck.
The skin changes of acanthosis nigricans (ak-an-THOE-sis NIE-grih-kuns) typically occur in people who are obese or have diabetes. Children who develop the condition are at higher risk of developing type 2 diabetes. Rarely, acanthosis nigricans can be a warning sign of a cancerous tumor in an internal organ, such as the stomach or liver.
Disease statistics: In 2002-03, 0.001% (178) of hospital consultant episodes were for acanthosis nigricans in england. 100% of hospital consultant episodes for acanthosis nigricans required hospital admission and 44% of hospital consultant episodes for acanthosis nigricans were for men and 56% were women, 3% required emergency services. 51 is the mean age of occurance, 54% occured in 15-59 year olds and 15% in over 75.