Blastocystis hominis is a microscopic organism that may be found in the stools of healthy people who aren't having any digestive symptoms. Blastocystis hominis is also sometimes found in the stools of people who have diarrhea, abdominal pain or other gastrointestinal problems.
Symptoms: Signs and symptoms that might be associated with blastocystis include: Diarrhea Nausea Abdominal cramps Bloating Excessive gas (flatulence) Hives Loss of appetite Fatigue
Treatment:Treatment of Blastocystis infection remains a complicated issue. Because there is still a great deal of debate about the true pathogenicity of Blastocystis, there is still much debate about the need for treatment. Further knowledge about the genotyping and subtyping of Blastocystis and the impact that various subtypes may have on pathogenicity and antimicrobial efficacy is still being sought . In a symptomatic patient, isolation of cysts in stool specimens should trigger a thorough evaluation for other causes of the patient’s gastrointestinal tract complaints, given the possibility for coinfection with other pathogens.
Iodoquinol has also been used to treat B. hominis infections in several studies. However, its efficacy has always been poor. Grossman reported that 23/56 (41%) of patients had B. hominis eradicated after a course of 650 mg TID for 20 days (11). Markell and Udkow noted that iodoquinol 650 TID for 10 to 20 days failed to eradicate B. hominis in 25 of 25 patients (18). With its poor in vitro performance noted above, this drug is probably not a good choice for the treatment of B. hominis.