Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest and can lead to a variety of emotional and physical problems. Symptoms of depression are Feelings of sadness, emptiness, angry outbursts, Sleep disturbances, Changes in appetite, Anxiety, Trouble thinking, making decisions etc.
According to Canadian Community Health Survey (CCHS) on Mental Health, 5.4% of the Canadian population aged 15 years and over reported symptoms of mood disorder in the previous 12 months, including 4.7% for major depression and 1.5% for bipolar disorder. Further, almost one in 8 adults (12.6%) identified symptoms of mood disorder at some point during their lifetime, including 11.3% for depression and 2.6% for bipolar disorder.
To diagnosis Depression various tests like Physical test, Lab tests, Psychological test, Diagnostic and Statistical Manual of Mental Disorders (DSM-5) can be conducted. Medications and psychological counseling (psychotherapy) are very effective for most people with depression. Selective serotonin reuptake inhibitors (SSRIs), Serotonin-norepinephrine reuptake inhibitors (SNRIs), Norepinephrine-dopamine reuptake inhibitors (NDRIs), Atypical antidepressants etc. antidepressant drugs can be used.
Many scientists work comes in on neurochemical processes in depression, in preclinical animal models of depression and finding the effect of the ketamine in treating depression. Some are looking at the relationship between the brain’s circuits and mood disorders such as depression.