Dissociative disorders are characterized by an involuntary escape from reality characterized by a disconnection between thoughts, identity, consciousness and memory.
Tests can be performed with symptoms like memory loss and a sense of unreality for example, head injury, brain lesions or tumours, sleep deprivation or intoxication. Diagnosis can be made with the help of interviews such as the Dissociative Disorders Interview Schedule (DDIS) and the Structured Clinical Interview for DSM-IV Dissociative Disorders (SCID-D), or with the Dissociative Experiences Scale (DES) which is a self-assessment questionnaire. Some diagnostic tests have also been adapted and/or developed for use with children and adolescents such as the Children's Version of the Response Evaluation Measure (REM-Y-71), Child Interview for Subjective Dissociative Experiences, Child Dissociative Checklist (CDC), Child Behavior Checklist (CBCL) Dissociation Subscale, and the Trauma Symptom Checklist for Children Dissociation Subscale.
Treatment: Long-term psychotherapy that helps the patient to cover the multiple personalities into one personality. Hospitalization may be required if behavior becomes bizarre or destructive. Psychotherapies such as cognitive behavioral therapy (CBT) and dialectical behavioral therapy (DBT) Eye movement desensitization and reprocessing (EMDR) and Medications such as antidepressants can treat symptoms of related conditions.
Translational tools as applicable to autoimmune disorders: antibody-proteases as a generation of highly informative and unique biomarkers to monitor subclinical and clinical stages of demyelination in multiple sclerosis (MS) PPT Version |