alexa Pediatric thrombocytopenia | Canada| PDF | PPT| Case Reports | Symptoms | Treatment

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  • Pediatric thrombocytopenia

    Pathophysiology

    Pediatric Thrombocytopenia is a condition in which you have a low blood platelet count. Platelets (thrombocytes) are colorless blood cells that help blood clot. Platelets stop bleeding by clumping and forming plugs in blood vessel injuries. Thrombocytopenia often occurs as a result of a separate disorder, such as leukemia or an immune system problem. Or it can be a side effect of taking certain medications. It affects both children and adults. Thrombocytopenia may be mild and cause few signs or symptoms. In rare cases, the number of platelets may be so low that dangerous internal bleeding occurs. Treatment options are available.

  • Pediatric thrombocytopenia

    Disease statistics

    Remarkable presenting features were an incidence peak in the first 2 years of age and male predominance in patients <24 months of age. Three age groups with different recovery rates (P < 0.001) were established (2-12 months: 89.8%; 1-8 years: 71.3%; 9-18 years: 49.0%). Platelet count <10 x 10(9)/L and history of previous illness were associated with higher remission rates only in patients >12 months of age. The score developed by the NOPHO Group showed a predictive value of 83.9% for acute ITP. Spontaneous remission between 6 months and 11 years from diagnosis was achieved by 107 of 325 (32.9%) non-splenectomized children with chronic ITP, and in 44.9% of them between 6 and 12 months from diagnosis.

  • Pediatric thrombocytopenia

    Treatment

    Specific treatments for thrombocytopenia will be determined by your child’s physicians based on the cause and severity of the disease, as well as your child’s tolerance for medications, procedures and therapies. Mild cases may not require treatment and may resolve on their own. Blood transfusions with platelets or red blood cells are sometimes needed.

  • Pediatric thrombocytopenia

    Research

    Pediatric Thrombocytopenia is a condition in which there is a lower-than-normal number of platelets in the blood. It may result in easy bruising and excessive bleeding from wounds or bleeding in mucous membranes and other tissues.

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