Blood cancer review journals include a brief description on lymphoma and its related research which includes all types of blood cancer disorders. Lymphoma study into the determinants, occurrence, diagnosis, remedy, and prognosis of lymphoma is being performed. Hundreds of clinical tests are being designed or undertook at any granted time. Investigations may aim on productive means of remedy, better ways of treating the disease, improving the value of life for patients, or appropriate care in remission or after cures.
Blood cancer is the second leading cause of cancer-related deaths and is the most common cancer among women, excluding non-melanoma skin cancers. An estimated 232,340 new cases of invasive breast cancer are expected among American women. The nuclear receptors, Estrogen receptor (ER) and progesterone receptor (PR) and their associated steroid hormones are play an important role in the development, differentiation and function of normal breast and endometrial cells. There is strong evidence that estrogen plays an essential role in the growth of breast tumors and the status of these hormones is employed as diagnostic indicators for endocrine responsiveness and tumor recurrence. The estrogen receptors (ERs) remain one of the attractive targets in the treatment of breast cancer till date. Till date, the two subtypes of human ERs identified, ER-Î± and ER-Î² have different tissue distribution pattern and transcriptional activity. One way of blocking the estrogen action on tumor cells is preventing the binding of estrogen (E2) to estrogen receptor (ER) by designing novel inhibitors of ER capable of blocking E2 without showing any estrogenic activity on their own.E2 and its derivatives are used by millions of women in Harmone Replacement Therapy (HRT) for the treatment of peri- and post-menopausal related symptoms.
Last date updated on June, 2014