alexa Kawasaki Disease |OMICS International| Journal Of Clinical And Experimental Cardiology

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Kawasaki Disease

Kawasaki disease is the most prevalent systemic vasculitis, and affects middle-sized arteries including coronary arteries, of children in developed countries. Kawasaki disease is a rare childhood illness that affects the blood vessels.In acute phase of Kawasaki disease, ample cytokines are known to increase, but the precise pathophysiology of Kawasaki disease remains unknown. In a recent report, a functional single nucleotide polymorphism (itpkc_3) in the inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) gene, a negative regulator of T-cell activation, was significantly associated with Kawasaki disease susceptibility and also with an increased risk of coronary artery lesions in both Japanese and United States children. However, little is known about the role of dendritic cells (DC), highly specialized antigen presenting cells initiating and regulating T cell response in the pathophysiology of acute Kawasaki disease. Suda K, Circulating Myeloid Dendritic Cells is Decreased in the Acute Phase of Kawasaki Disease.
  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger

Last date updated on July, 2014