Coarctation of the aorta (CoA) is a relatively common defect that accounts for 5-8% of all congenital heart defects. Coarctation of the aorta may occur as an isolated defect or in association with various other lesions, most commonly bicuspid aortic valve and ventricular septal defect (VSD). It imposes significant afterload on the left ventricle (LV), which results in increased wall stress and compensatory ventricular hypertrophy.
Treatment in patients with Aortic Coarctation includes the use of diuretics and inotropic drugs. Prostaglandin E1 (0.05-0.15 mcg/kg/min) is infused intravenously to open the ductus arteriosus. Ventilatory assistance is provided to patients with markedly increased work of breathing. Infusion of inotropic drugs (dopamine, dobutamine, epinephrine) is useful when ventricular dysfunction is present, especially with hypotension. A Foley catheter is inserted to monitor renal perfusion and urine output.
Coarctation of the aorta in china accounts for about 4 to 6 percent of all congenital heart defects with a reported prevalence of about 4 per 10,000 live births.It occurs more commonly in males than in females (59 versus 41 percent). Most cases are sporadic. Presence and severity of aortic coarctation increases with age reaching 20% prevalence in the oldest age.