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Churg-Strauss Syndrome

  • Churg-Strauss syndrome

    Churg-Strauss syndrome is a rare disorder that affects multiple organs especially the lungs. It is characterized by the abnormal clustering of certain white blood cells (hypereosinophilia) in the blood and tissues, inflammation of blood vessels (vasculitis), and the development of inflammatory nodular lesions called granulomas (granulomatosis). Most of the affected individuals have a previous history of allergy. Asthma and other lung abnormalities often precede the development of the generalized (systemic) symptoms and findings seen in Churg-Strauss syndrome by as little as six months or as much as two decades.

  • Churg-Strauss syndrome

    Disease Statistics

    Churg-Strauss disease is said to account for slightly more than 2% of all vasculitic illnesses. The various primary systemic vasculitides (Churg-Strauss disease, PAN, microscopic polyangiitis, Wegener granulomatosis) together are estimated to affect 15-25 individuals per million individuals in North America annually. Little information is available concerning international variation in the prevalence or incidence of Churg-Strauss disease.

  • Churg-Strauss syndrome

    Current Research

    The ongoing research work related to Churg-Strauss syndrome include A Double-blind, Randomised, Placebo-controlled Study to Investigate the Efficacy and Safety of Mepolizumab in the Treatment of Churg-Strauss syndrome in Subjects Receiving Standard of Care Therapy, Cytokine production profile of CD4+ T cells from patients with active Churg-Strauss syndrome tends toward Th17, Longitudinal Protocol for Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) etc…

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