Pathophysiology: Down syndrome (DS), also called Trisomy 21, is a condition in which extra genetic material causes delays in the way a child develops, both mentally and physically. Symptoms • Flattened facial features • Small head • Short neck • Protruding tongue • Upward slanting eyes, unusual for the child's ethnic group • Unusually shaped or small ears • Poor muscle tone • Broad, short hands with a single crease in the palm • Relatively short fingers and small hands and feet • Excessive flexibility • Tiny white spots on the colored part (iris) of the eye called Brushfield spots • Short height.
Treatment: Regular medical checkups, helping child develop, watching for early signs of health problems, and finding support. With treatment and support, you can help child live a happy, healthy life. Major Research: Study led by Temple researchers reveals new link between Down syndrome and Alzheimer's.