Focal segmental glomerulosclerosis also known as Focal And Segmental Hyalinosis, Focal Glomerular Sclerosis, Focal Glomerulosclerosis, Focal Segmental Glomerulonephritis, Focal Sclerosis With Hyalinosis, Segmental glomeruloclerosis, Focal Nodular Glomerulosclerosis
Focal segmental glomerulosclerosis is a cause of nephrotic syndrome in children and adolescents, as well as an leading cause of kidney failure in adults. It accounts for about a sixth of the cases of nephrotic syndrome Lupus. It may be caused due to the following reasons like Drugs such as heroin, bisphonsphonates.
Focal segmental glomerulosclerosis in the early stages characterised by symptoms like Fatigue, a poor appetite, headache, itchy skin, shortness of breath and/or nausea. Due to this the patient may gain weight and also causes severe pain, Abnormally high protein content in the urine (proteinuria ). Or they may show a low level of protein in the blood (hypoproteinemia), High cholesterol, High blood pressure.
In recent years in china, the morbidity of primary FSGS have an increasing tendency according to reports.FSGS NOS was also the most common variant seen in one institution in China (55.9%) with tip and collapsing variants accounting for 4.8% and 6.9% of cases, respectively. FSGS has slowly increased to a rate of approximately five cases/million population in 2003.