Nephrotic syndrome is a condition in which your kidneys “leak” protein from your blood into your urine. In children, nephrotic syndrome may only be temporary, or it may be an early sign of kidney damage. The most common type of nephrotic syndrome in children is called minimal change disease. With minimal change disease, there are very tiny physical changes in the tiny filters (called glomeruli) in the kidneys. These tiny changes can affect how the kidneys work. Minimal change disease can usually be treated with a medicine called prednisone, but this type of nephrotic syndrome can come back.
About 75 per cent of cases with nephrotic syndrome are caused by primary glomerular diseases. In children nearly 80 per cent of cases are nephrotic syndrome of minute lesion type. The rest are secondary to other diseases. Renopuncture biopsy is of much help in confirming the cases of the diseases and indicating treatment. If your child has nephrotic syndrome, you may notice swelling around his or her eyes, face, ankles or feet. The type of treatment your child will need depends on the type of nephrotic syndrome he or she has. For minimal change disease, the most common treatment is prednisone, a type of steroid. Prednisone helps to keep protein from leaking into your child’s urine.