alexa New born jaundice | China| PDF | PPT| Case Reports | Symptoms | Treatment

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New Born Jaundice

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  • New born jaundice

    Hepatic excretory capacity is low both because of low concentrations of the binding protein ligandin in the hepatocytes and because of low activity of glucuronyl transferase, the enzyme responsible for binding bilirubin to glucuronic acid, thus making bilirubin water soluble (conjugation).Neonatal hyperbilirubinemia, defined as a total serum bilirubin level above 5 mg per dL (86 μmol per L), is a frequently encountered problem.

  • New born jaundice

    Neonatal hyperbilirubinemia, defined as a total serum bilirubin level above 5 mg per dL (86 μmol per L), is a frequently encountered problem. Although up to 60 percent of term newborns have clinical jaundice in the first week of life, few have significant underlying disease.1,2 However, hyperbilirubinemia in the newborn period can be associated with severe illnesses such as hemolytic disease, metabolic and endocrine disorders, anatomic abnormalities of the liver, and infections.

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