Pulmonary Valve Stenosis

Pulmonary valve stenosis is a condition characterized by obstruction to blood flow from the right ventricle to the pulmonary artery. This obstruction is caused by narrowing (stenosis) at one or more points from the right ventricle to the pulmonary artery. The most common form of pulmonary stenosis is obstruction at the valve itself, referred to as pulmonary valvar stenosis.

Pulmonary valve stenosis signs and symptoms vary, depending on the extent of the obstruction. People with mild pulmonary stenosis usually don't have symptoms. Pulmonary valve stenosis signs and symptoms may include Heart murmur - an abnormal whooshing sound heard using a stethoscope, caused by turbulent blood flow, Shortness of breath, especially during exertion, Chest pain, Loss of consciousness (fainting), Fatigue.

Statistical analysis on pulmonary valve stenosis in china resulted as of 547 infants, 103 (18.8%) experienced 116 episodes of LRTIs (incidence=0.84 LRTIs/100 child-weeks). Most (81%) episodes were bronchiolitis. Forty-nine (9.0%) infants were hospitalized at least once with an LRTI. There were 53 hospitalizations (45.7%) for 116 LRTI episodes. None of these infants were breastfed. The odds of LRTI in infants whose mothers had CD4%<14 were 4.4 times than that of those whose mothers had CD4%≥29 (p=0.003). The odds of LRTI were 16.0 times that of infants with a CD4+ count [cells/mm3] < 750 at birth compared to those with CD4+≥750 (p=0.002). Maternal CD4+ decline and Infant hemoglobin at the 6-12 week visit were associated with infant LRTIs after 6-12 weeks and before six months of age.