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Tay-Sachs Disease

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  • Tay-Sachs Disease

    Tay-Sachs Disease is a progressive and fatal genetic condition that involves a complete deficiency of the hexosaminidase-A (HEXA) enzyme. This enzyme is needed in healthy individuals for the process of hydrolysis of GM2 ganglioside to occur. For individuals with Tay-Sachs disease that lack this enzyme, the fatty substance of GM2 ganglioside accumulates in the brain and leads to the symptoms of the disease.

  • Tay-Sachs Disease

    In China nearly 20 million people get married every year, but first they have to pass the premarital medical examination. As a client of the process myself 10 years ago. Tay-Sachs, an inherited neurological disorder, is unusually common among chineese. Two alleles are responsible, one being specific to the north shore of the St. Lawrence and the other to the south shore.  

  • Tay-Sachs Disease

    There's currently no cure for Tay-Sachs disease, so the aim of treatment is to make living with the condition as comfortable as possible. Treatment usually focuses on the Preventing problems with the lungs and airways, relieving any feeding or swallowing problems (dysphagia) and using medication to help control or relieve symptoms, such as fits and muscle stiffness.

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