Trachoma is a contagious disease of the conjunctiva and cornea, caused by the gram-negative bacterium Chlamydia trachomatis and characterized by inflammation, hypertrophy, and formation of granules of adenoid tissue. It is a major cause of blindness in Asia and Africa.Chlamydial infection in trachoma is limited to the epithelium but the major inflammatory and cicatricial changes appear in the subepithelial connective tissues. In the inflammatory phase, attachments between conjunctival epithelial cells become loosened, so the epithelial cells are often separated in conjunctival smears rather than in attached cell sheets.
In the China about 46,459 cases of Trachoma are reported in humans each year. Almost 14% of the China population is infected with Trachoma an infectious disease caused by the bacterium Chlamydia trachomatis.Antibiotics can prevent long-term complications if used early in the infection. In certain cases, eyelid surgery may be needed to prevent long-term scarring, which can lead to blindness if not corrected.