St. Jude Children's Research Hospital Faculty
Department of Biostatistics
BS - Beijing Computer Institute, China (1984) PhD - Texas A & M University (1993)
He collaborate with St. Jude investigators in the areas of hematological malignancies,pharmaceutical sciences, molecular pathology,bioinformatics, and computational biology. He is interested in statistics methodological research in several areas with applications to biomedical sciences.Statistical inference methods in systems biology and genome-wide integrated analysis, with emphasis on applications to cancer genomics.Validation inference in genome-wide studies.Estimation and control of false discovery rates; assessment of statistical significance in massive multiple comparisons applied to biomedical research, such as genome-wide studies.Analysis of high-dimensional and large data sets, data mining, dimension reduction and visualization, variable (feature) selection for cluster analysis, modeling, and classification.Methodologies of multivariate analysis: nonparametric methods combining linear or nonlinear projections and function estimation. Applications of percentiles (quantiles) in data analysis and modeling.Methods of analyzing general distance (similarity) and non-dimensional data, visualization, cluster analysis, and multidimensional scaling.