Thomas Jefferson University
Michael Holinstat is an assistant professor of Medicine at Thomas Jefferson University in Philadelphia. He received his Ph.D. in Pharmacology from the University of Illinois at Chicago and postdoctoral training at Vanderbilt University in the Department of Pharmacology. His research focuses on identifying novel approaches to anti-platelet therapy with a special emphasis on regulation of platelets through the lipoxygenase pathway leading to a number of oxidized fatty acids which may play a central role in regulating unwanted platelet activation. Additionally, the lab studies regulation of platelet signaling through PAR1 and PAR4.
Thrombosis; Rap1; Gpcr; Signal Transduction; Platelet; Pharmacology; Hematology; Medicine; Small G Protein; Signal Transduction; Signaling; Lipoxygenase; 12-Lipoxygenase; 12-HETE; 12-HETrE.