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Nicolai Doliba

Nicolai Doliba

Assistant Professor
University of Pennsylvania, USA
Tel: 215-898-4366

Biography

Research

My research has focused on the role of bioenergetics, ion transport and metabolic coupling factors in nutrient- and drug-stimulated insulin release at normal conditions and during diabetes mellitus. Using combinations of different methods and approaches, including 31P, 13C, and 1H Nuclear Magnetic Resonance Spectroscopy techniques, polarographic and phosphorescence methods of measuring O2 consumption, Ca2+ imaging and others, I attempt to directly address the essential mechanisms of stimulus-secretion coupling in pancreatic islets.