Louisiana State University Health
Shile Huang began to study the role of mTOR signaling in cancer cell survival/apoptosis during my postdoctoral training, mentored by Dr. Peter J. Houghton at St. Jude Children’s Research Hospital. Since starting the laboratory in Louisiana State University Health Sciences Center in July 2003, He have been studying how mTOR regulates tumor cell motility and how curcumin inhibits mTOR signaling. The laboratory has considerable experience in studying anticancer mechanisms of small molecules, and has generated/collected a variety of reagents (stable cell lines, and adenoviral, retroviral and lentiviral constructs) related to mTOR pathways. He have a record of successful and productive research projects. So he have the expertise necessary to successfully carry out the proposed work.
mTOR signaling in tumorigenesis and metastasis; anticancer mechanisms of natural products; neurotoxicity of cadmium.