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Soraya L. Valles

Soraya L. Valles

Department of Physiology
School of medicine
University of Valencia


In 1990 I graduated in Biological Science at the University of Valencia and remained there to undertake a PhD under the supervision of Consuelo Guerri at Research Institution (Instituto de Investigaciones Citolgicas), which I completed in 1996. During my PhD my dissertation was Changes of astroglia intermediate filaments gene expression during rat brain development: Effect of alcohol exposure. I analyze the events which occur during the early stages of astrogliogenesis during brain development, using in vivo and in vitro experiments. I did experiments in cells in culture primary as radial glia (stem cells in brain), astrocytes and neurons.
In 1997 I joined Eva Qwanstroms group at the Hallamshire Hospital (University of Sheffiel) in Sheffield, UK and spent three years involved in the identification of an adhesion-regulated subunit of the interleukin-1 (IL-1) receptor complex. I was working in immunology, cytokines, inflammation processes and matrix regulation of IL-1 responses.
In 2000 I returned to Spain at Department of Physiology, Medicine Faculty of Valencia. University of Valencia and I were appointed to a part-time position as Lectureship. In 2004 I was appointed to a fixed-term position as permanent University Lecturer at this department in the University of Valencia. During this time I was involved in the mechanisms of oxidative stress in the generation of Alzheimer’s disease with Jose Vintildes group. Also at this time I developed my lectures with Luis Such group with who I learned a lot about physiology and how to do a correct lecturer to pupils in my our department.
At this moment I work in Alzheimer’s diseases and in inflammation and oxidative stress mechanisms. Also I would like to work in precursor cells and the subsequently ability to further differentiate into neurons and astrocytes inside the brain. I order a grant from my sanity government and I still waiting for the resolution grant, about stem cells and brain.


Physiology & Alzheimer’s diseases and in inflammation and oxidative stress mechanisms.