Department of Medicine
University of California, USA
Chaban is Director of Clinical and Translational Research Center; "Accelerating Excellence in Translational Science" (AXIS) at Charles R. Drew University of Medicine and Science (CDU) and Associate Professor of Medicine at the Department of Medicine, University of California, Los Angeles (UCLA). He serves as Co-Leader of Research Education, Training and Career Development Program of UCLA Clinical and Translational Science Institute. Dr. Chaban’s area of expertise includes endocrine regulations of nociception as well as gender difference in pain perception. He serves as Editor for International Journal of Research in Nursing and as Executive Editor of Journal of Autacoids.
The primary focus of my research program is to elucidate the nociceptive pathways modulated by circulating and local hormones in nervous tissue. While a central site of this modulation has been widely accepted, I have continued to investigate how they act on primary nociceptors and modulate the response to pro- and anti-nociceptive signals, depending upon the nature of the signals interacting at the level of sensory neurons. Nociceptive systems are implicated in the etiology of functional disorders such as non- cardiac chest pain, interstitial cystitis, fibromyalgia, acute or chronic abdominal pain associated with functional bowel disorders, chronic pelvic pain and others. Our studies may provide important information about the actions of hormones on primary sensory neurons for a better understanding the clinical presentation of functional pain-associated disorders.