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conferenceseries
.com
Volume 8, Issue 9 (Suppl)
J Clin Exp Cardiolog, an open access journal
ISSN: 2155-9880
Euro Cardiology 2017
October 16-18, 2017
October 16-18, 2017 | Budapest, Hungary
20
th
European
Cardiology
Conference
J Clin Exp Cardiolog 2017, 8:9(Suppl)
DOI: 10.4172/2155-9880-C1-078
Cryoablation of atrial fibrillation and antiarrhythmic drug pretreatment: A single referral center
experience
Michael Spartalis
1
, Eleni Tzatzaki
1
, Eleftherios Spartalis
2
, Demetrios Moris
3
, Ilias Doulamis
2
, Andreas S Triantafyllis
4
, Efthimios Livanis
1
and
George
Theodorakis
1
1
Onassis Cardiac Surgery Center, Greece
2
University of Athens, Greece
3
The Ohio State University Comprehensive Cancer Center, USA
4
University Hospitals Leuven, Belgium
Background:
Pulmonary vein isolation (PVI) ablation has emerged as the gold standard of ablative strategies to treat medically
refractory paroxysmal and persistent atrial fibrillation (AF). Regardless of the superiority of catheter ablation based on PVI
over antiarrhythmic drug therapy, recurrence rates of AF remain higher than desired. Our objective was to assess the safety and
efficacy of cryoablation in a single referral center.
Methods:
This is a retrospective analysis of results after cryoablation treatment of AF over three years. 146 patients with AF
underwent a cryoablation procedure in our clinical center and were followed-up for three years after the procedure.
Results:
Cryoablation was clinically successful in 90.83% of the patients with paroxysmal AF and 60% of those with persistent
AF. The clinical success of cryoablation was correlated with pretreatment with amiodarone and in the case of re-ablation. With
respect to postoperative complications, major bleeding was correlated with female gender, treatment with rivaroxaban and
amiodarone.
Conclusion:
Freedom from recurrent AF is about 65% with follow-up limited to 1 to 2 years in major trials. We present a
durable event free result in most patients out to 3 years with better outcomes than previously reported.
msparta@med.uoa.gr