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Volume 8 Pediatrics & Therapeutics
ISSN: 2161-0665 Pediatrics and Pediatric Gastroenterology 2018
March 21-22, 2018
16th Annual World Congress on
3rd Annual World Congress on
March 21-22, 2018 | New York, USA
PEDIATRICS
PEDIATRIC NUTRITION,
GASTROENTEROLOGY & CHILD DEVELOPMENT
&
Maternal risk factors associated with retinopathy of prematurity among patients in east avenue medical
center from 2010 to 2015
Ida Fidelis Denosta and Carina Cruz-Quimbo
East Avenue Medical Center, Philippines
Aim: The aim of this study is to determine the maternal risk factors associated with the development of retinopathy of prematurity
(ROP).
Design: A retrospective cohort study.
Setting: The study was done in a tertiary government hospital.
Patients: This study included admitted premature neonates in neonatal intensive care unit (NICU) who underwent ROP screening.
All patients with congenital abnormality of the eyes were excluded in the study.
Methodology: List of admitted premature patients who underwent ROP screeningwas collectedwithin the study period. Demographic
data was collected from the patient’s medical records.
Statistical Analysis: Descriptive statistics were presented for categorical outcome measures. Wilcoxon rank sum test was used to
compare two averages. Chi-square test, Yates’ Chi-square test and Fisher’s exact test were used to compare proportions. Univariate
and multivariate regression analyses were used to estimate crude and adjusted odds-ratios, corresponding 95% CI and based on
p-value ≤0.05 statistical significance.
Result: This study showed 57% cases of ROP, majority with Stage 1 (66%), mostly female infants (53.4%; p<0.001), mildly asphyxiated
(51.2%, p=0.290; 77.2%, p=0.117) and were small for gestational age (57.3%; p<0.001). On the average, these infants underwent
one day of either invasive or non-invasive mechanical ventilation, two days with FiO2 of >0.5 liters per minute, had two blood
transfusions, and with shorter hospital stay (17 vs 26 days; p<0.001). The average age of mothers who delivered infants with ROP was
26 years old, multipara (59.2%), and underwent normal spontaneous delivery (67%). About half reported adequate prenatal check-
ups (53.8%), and diagnosed with urinary tract infection (40.1%).
Conclusion: Data showed that mothers with urinary tract infection and preeclampsia are more likely to deliver infants with
retinopathy of prematurity thus a significant maternal risk factors of ROP.
Pediatr Ther 2018, Volume: 8
DOI: 10.4172/2161-0665-C1-049