Advent of Microfluidics

Scaffolds are important part of tissue engineering. For a material to be certified as biomaterial of interest we need to test its bio-compatibility and cytotoxicity. Traditional methods are time consuming and do not offer in vivo conditions. A recent technology called Microfluidic technology allows to study cells in in-vivo condition with control of the fluid supply. Micro and sub-micrometer microfluidic channels are developed in patterns that control the flow, mixing of solutions and supply of nutrients. Another approach is developing a lithographic technique to manufacture microfluidic structures enclosed in a calcium alginate hydrogel seeded with cells.

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