Aging and Aging Biology

Aging can be defined as the time-related deterioration of the physiological functions necessary for survival and fertility. Aging is both inevitable and universal but the mysteries that control human life span are yet to be discovered. But it is believed that the aging might be due to Telomere Shortening,   DNA Damage resulting in decline in cellular regenerative capacity of all tissues and organs. Accumulations of senescent cells were found in vivo in mammals with increasing age, and at sites of age-related pathology. And hence cellular senescence may be considered as the cellular model of organismal aging. Aged individuals encounters several neurological and cardio vascular diseases along with many endocrine disorders. Recent studies depicted that stem cell therapy is the best alternative to cure many age related disorders and extensive research has been focused in this area.

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