Antibiotics by Drug origin

The first economically available antibacterial was Prontosil, a sulfonamide improved by the German biochemist Gerhard Domagk in the 1930s. Before this, in 1928, Alexander Fleming had invented the first antibiotic, penicillin, but it took over a decade before penicillin was introduced as a treatment for bacterial infections. This was possible through the work of Florey and Chain who managed to purify the antibiotic and scale-up production efficiently. The introduction of penicillin considered the beginning of the so-called “golden era” of antibiotics. Between 1940 and 1962, most of the antibiotic classes we use as medicines today were invented and recommended to the market. Each class typically consists of several antibiotics that have been discovered over time or are modified versions of previous types. Such as different penicillins and cephalosporins.

The first economically available antibacterial was Prontosil, a sulfonamide improved by the German biochemist Gerhard Domagk in the 1930s. Before this, in 1928, Alexander Fleming had invented the first antibiotic, penicillin, but it took over a decade before penicillin was introduced as a treatment for bacterial infections. This was possible through the work of Florey and Chain who managed to purify the antibiotic and scale-up production efficiently. The introduction of penicillin considered the beginning of the so-called “golden era” of antibiotics. Between 1940 and 1962, most of the antibiotic classes we use as medicines today were invented and recommended to the market. Each class typically consists of several antibiotics that have been discovered over time or are modified versions of previous types. Such as different penicillins and cephalosporins.

  • Pre-Antibiotic Era
  • Foundation of the Antibiotic Era - Antibiotic Resistance
  • Improvement of Antimicrobials
  • Environmental Resistome

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