Antibiotics for Emerging and Re-emerging Diseases

New diseases are arising worldwide and old diseases are re-emerging as Infectious agents evolve or spread, and as changes occur in ecology, socioeconomic conditions, and population patterns. Likewise, many diseases thought to be adequately controlled appear to be making a comeback. In developed countries, public health measures such as sanitation, sewage treatment, vaccination programs, and access to good medical care-including a wide range of antibiotics-have virtually eliminated “traditional” diseases such as diphtheria, whooping cough, and tuberculosis.

The microbial world is complex, dynamic and constantly evolving. Infectious agents reproduce rapidly, mature frequently, cross the specific barrier between animal hosts and humans, and adapt with relative ease to their new environments. Because of these traits, infectious agents are able to alter their epidemiology, their virulence, and their susceptibility to anti-infective drugs.

When disease is caused by a microbe that is newly identified and not known previously to infect humans, it is commonly called emerging infectious diseases. When the disease is caused by an infectious agent previously known to infect humans that has re-entered human population or changed in epidemiology or susceptibility to anti-infective drugs, it is called as re-emerging infection.

  • Resistance and re-emerging theories
  • Medication procedures
  • Molecular mechanism of resistance
  • New drugs for emerging diseases

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