Atherosclerosis Risk Factors

Many factors lead to the risk for atherosclerosis. Some risks can be prevented, while others cannot. Atherosclerosis is a slow, progressive disease that may begin as early as childhood. Although the exact cause is unknown, it may start with damage, injury or hardening of the inner layer of an artery. The common causes for hardening of the arteries are high cholesterol, fat, aging, smoking, high blood pressure etc.

Many factors lead to the risk for atherosclerosis. Some risks can be prevented, while others cannot. Atherosclerosis is a slow, progressive disease that may begin as early as childhood. Although the exact cause is unknown, it may start with damage, injury or hardening of the inner layer of an artery. The common causes for hardening of the arteries are high cholesterol, fat, aging, smoking, high blood pressure etc.

Cholesterol - According to the low-density-lipoprotein (LDL) receptor hypothesis, development of atherosclerosis is caused by a high concentration of LDL-cholesterol in the blood, and lowering LDL-cholesterol reverses, or at least retards, atherosclerosis, thus preventing cardiovascular disease.

High Blood Pressure - People with high blood pressure are more likely to develop coronary artery disease, because high blood pressure puts added force against the artery walls. Over time, this extra pressure can damage the arteries, making them more vulnerable to the narrowing and plaque build-up associated with atherosclerosis. The narrowed artery limits or blocks the flow of blood to the heart muscle, depriving the heart of oxygen. When the process is advanced enough, patients can experience angina, or chest pain, when they exert themselves. The hardened surface of the artery can also encourage the formation of small blood clots, potentially leading to a heart attack or stroke.

Diabetes - Atherosclerosis is the cause of a majority of cardiovascular events, and atherosclerosis is accelerated by diabetes and the metabolic syndrome. Many risk factors are associated with the metabolic syndrome and help explain the increased cardiovascular disease (CVD) in that condition. Because the metabolic syndrome occurs in most people with type 2 diabetes, its presence likely accounts for most of the increased incidence of CVD in type 2 diabetes. However, the presence of diabetes increases the risk of CVD beyond that seen with the metabolic syndrome alone. Moreover, CVD risk is increased in type 1 diabetes, in which the presence of the metabolic syndrome and these other risk factors is less common.

Obesity - Obesity is an independent risk factor for the development of cardiovascular atherosclerosis. An individual with a body mass index (BMI) of greater 30 kg/m2 is four times more likely to suffer from cardiovascular disease than an individual with a BMI of 25 kg/m2or less. Currently, around 20% of the adult population in Europe is obese; as a consequence as the twenty-first century unfolds, obesity will become an increasingly important factor in the pathogenesis of cardiovascular atherosclerosis. A critical early event in the pathogenesis of atherosclerosis is endothelial cell dysfunction, a key feature of which is reduced bioavailability of the signalling molecule, nitric oxide (NO). It is now well established that obesity is associated with endothelial dysfunction.

Smoking & other tobacco use - Smoking is a major cause of CVD. Smoking has been responsible for approximately 140,000 premature deaths annually from CVD. More than 1 in 10 deaths worldwide from CVD in 2000 were attributed to smoking. In the United States, smoking accounted for 33 % of all deaths from CVD and 20 % of deaths from ischemic heart disease in persons older than 35 years of age. Smoking also influences other cardiovascular risk factors, such as glucose intolerance and low serum levels of high-density lipoprotein cholesterol.

Homocysteine - Elevated homocysteine is a known risk factor for cardiovascular disease and thrombosis. It has also been shown to be associated with micro albuminuria which is a strong indicator of the risk of future cardiovascular disease and renal dysfunction. Homocysteine degrades and inhibits the formation of structural components of arteries - collagen, elastin and proteoglycans. Chronic consumption of alcohol may also result in increased plasma levels of homocysteine. Deficiencies of the vitamins B6, B9 and B12 can lead to high homocysteine levels. 

  • Cholesterol
  • Diabetes
  • High Blood Pressure
  • Obesity
  • Smoking & Tobacco Usage
  • Homocysteine

Related Conference of Atherosclerosis Risk Factors

July 05-06, 2018

26th Annual Conference on Clinical & Medical Case Reports in Cardiology

Golden Tulip Berlin – Hotel Hamburg
July 05-06, 2018

3rd International Conference on Cardiovascular Medicine and Cardiac Surgery

Golden Tulip Berlin – Hotel Hamburg
September 10-11, 2018

4th International Conference on Hypertension & Healthcare

Zurich, Switzerland (Hilton Zurich Airport)
September 11-12, 2018

World Cardiology and Cardiologist Meeting

Stockholm, Sweden
September 14-15, 2018

4th Global Summit on Heart Diseases

Singapore
17-18 September,2018

24th World Cardiology Conference

Hong Kong
September 17-18,2018

25th Annual Cardiologists Conference

Hong Kong
September 20-21, 2018

9th International Conference on Cardiac Surgery

Oslo, Norway
September 21-22, 2018

27th International Conference on Clinical & Experimental Cardiology Research

Vancouver, British Columbia, Canada
September 24-26, 2018

5th World Heart and Brain Conference

Abu Dhabi, UAE
October 05-06, 2018

American Heart Congress - CVD

Los Angeles, California, USA
October 22-23, 2018

Global Cardiology Summit

Osaka, Japan
Oct 22- Oct 24 , 2018

27th European Cardiology Conference

Rome, Italy
October 22-24, 2018

27th European Cardiology Conference

Rome, Italy
November 5-6, 2018

28th World Congress on Cardiology and Heart Diseases

Amsterdam, Netherlands
November 15-17, 2018

World Heart Rhythm Conference

Istanbul, Turkey
November 19-20, 2018

29th World Cardiology Conference

Edinburgh, Scotland
November 21 - 22, 2018 |

6th World Congress on Hypertension and Public Health

Paris, France
April 29- 30, 2019

World Heart Congress 2019

London, UK
February 18-19, 2019

30th European Heart Diseases and Heart Failure Congress

Amsterdam, Netherlands
March 18-20, 2019

Middle East Heart Congress

Dubai, UAE
March 28- 29, 2019

5 th World Heart Congress

Osaka, Japan
April 19-20,

World Heart and Brain Congress

Chicago, USA

5th World Heart Congress

April 22-23, 2019 Paris, France
April 25-26, 2019

7th International Conference on Hypertension & Healthcare

Helsinki, Finland
April 29 - May 01, 2019

4th World Heart Congress

Kyoto, Japan
June 17-19, 2019

31st Annual Cardiologists Conference

Rome, Italy

Atherosclerosis Risk Factors Conference Speakers

Recommended Sessions

Related Journals

Are you interested in