Autoimmunity and Women


The majority of people living with autoimmune disorders are women, usually those who are of childbearing age. In fact, autoimmune diseases are among the leading causes of death and disability in girls and women 65 years of age and younger.There are many different types of autoimmune diseases, which occur when the immune system mistakenly attacks the body's own organs and tissues. The majority of these diseases are far more common in women than in men — an estimated 75 percent of those living with autoimmune diseases are female. Immune systems tend to be more sophisticated then men's, because Women naturally have stronger inflammatory responses than men when their immune systems are triggered, and inflammation plays a key role in many autoimmune diseases, or hormonal differences. Two X chromosomes in contrast to men’s X and Y chromosome, after a pregnancy or fatal cells can remain in circulation in a woman's body for years. 

 Autoimmune diseases strike women three times more than men. Some diseases have an even higher incidence in women. Autoimmune diseases have been cited in the top ten leading causes of all deaths among U.S. women .Autoimmune diseases can affect virtually every site in the body, including the endocrine system, connective tissue, gastrointestinal tract, heart, skin, and kidneys. At least 15 diseases are known to be the direct result of an autoimmune response, 

  • Sex Hormones
  • Gender Differences in Immunity
  • History of Pregnancy
  • Miscarriage Infertility
  • XX Chromosomal effect
  • Androgen deficiency
  • Genetic susceptibility

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