Blood-brain barrier

More than 100 years ago it was discovered that if blue dye was injected into the bloodstream of an animal, that tissues of the whole body except the brain and spinal cord would turn blue. To explain this, scientists thought that a "Blood-Brain-Barrier" (BBB) which prevents materials from the blood from entering the brain existed. The BBB is semi-permeable; that is, it allows some materials to cross, but prevents others from crossing. In most parts of the body, the smallest blood vessels, called capillaries, are lined with endothelial cells. Endothelial tissue has small spaces between each individual cell so substances can move readily between the inside and the outside of the vessel. However, in the brain, the endothelial cells fit tightly together and substances cannot pass out of the bloodstream.

The blood–brain barrier occurs along all capillaries and consists of tight junctions around the capillaries that do not exist in normal circulation. Endothelial cells restrict the diffusion of microscopic objects (e.g., bacteria) and large or hydrophilic molecules into thecerebrospinal fluid (CSF), while allowing the diffusion of small hydrophobic molecules (O2, CO2, hormones). Cells of the barrier actively transport metabolic products such as glucose across the barrier with specific proteins. This barrier also includes a thickbasement membrane and astrocytic endfeet

  • Neuromyelitis Optica
  • Cell based therapies
  • Immunomodulation
  • Brain-immune loop conjunction
  • Ion channel disorder
  • Disease confined to Blood Brain Barrier
  • Vascular Neurology

Related Conference of Blood-brain barrier

April 19-20, 2018

7th World Congress on Immunology

Amsterdam, Netherlands
May 16-17, 2018

World Congress on Allergy and Immunotherapy

Osaka, Japan
July 12-13, 2018

5th International Conference on Parasitology

Paris, France
September 13-14, 2018

World Conference on Vaccine and Immunization

Romania
September 13-14, 2018

11th Annual Congress on Immunology & Immunotechnology

Zurich, Switzerland
September 17-18, 2018

3rd International Conference on Tumor & Cancer Immunology and Immunotherapy

San Diego, California, USA
September 17-18, 2018

3rd International Conference on Tumor & Cancer Immunology and Immunotherapy

San Diego, California, USA
September 20-21, 2018

Global Meet on Immunology and Molecular Biology

Oslo, Norway
October 19-20, 2018

10th World Congress and Expo on Immunology

New York, USA
October 29-30, 2018

6th International Conference on HIV/AIDS, STDs and STIs

San Francisco, USA
November 26-27, 2018

3rd International Conference on Autoimmunity

Dublin, Ireland
December 05-06, 2018

4th Antibodies, Antibiotics and Bio Therapeutics Congress

Chicago, Illinois, USA
December 05-06-2018

Conference on Biostatistics and Informatics

Dubai, UAE

Blood-brain barrier Conference Speakers

Recommended Sessions

Related Journals

Are you interested in