Cancer Drugs and Vaccines

The main purpose of the drug is not only treating cancer, but also for relieving symptoms of the cancer such as pain and side-effects, such as nausea, commonly seen with the various types of treatment. Vaccines have been developed that prevent infection by some carcinogenic viruses. Human papillomavirus vaccine (Gardasil and Cervarix) decrease the risk of developing cervical cancer and helps in decresase in the risk of cancer. The hepatitis B vaccine prevents infection with hepatitis B virus and thus decreases the risk of liver cancer. The administration of human papillomavirus and hepatitis B vaccinations is advisable most commonly. Some cancer drugs are Cabazitaxel, Capecitabine, Carboplatin, and Cetuximab. Chemotherapy drug combinations are as such Cisplatin, Crizotinib. Most anti-cancer drugs act by inhibiting DNA synthesis in the cell growth cycle, because anti-cancer drugs generally affect rapidly dividing cells, other non-cancerous cells will also be affected. The site of the cells which is affected determines the side-effects of the individual drugs. Other cells affected include blood cells, which fight with the infection, helps in the blood clotting, and carry oxygen to all parts of the body. The movement the blood cells are affected, patients are more likely to get infected they may bleed very easily, and may feel weak and very tire. Rapidly dividing cells in hair roots, and cells that line the digestive tract, may also be affected.

The development of antibiotic resistance in particular stems from the drugs targeting only specific bacterial molecules. Because the drug is so specific, any mutation in these molecules will interfere with or negate its destructive effect, resulting in antibiotic resistance. Known as Drug delivery Conditions treated with combination therapy include tuberculosis, leprosy, cancer, malaria, and HIV/AIDS. One major benefit of combination therapies is that they reduce development of drug resistance, since a pathogen or tumor is less likely to have resistance to multiple drugs simultaneously. Artemisinin-based monotherapies for malaria are explicitly discouraged to avoid the problem of developing resistance to the newer treatment. Drug Induced Blood Disorders causes of sickle cell anemia,pale skin non steroids anti inflammatory drugs which causes ulcers Using drug repositioning, pharmaceutical companies have achieved a number successes, for example Pfizer's Viagra in erectile dysfunction and Celgene's thalidomide in severe erythema nodosum leprosum. Smaller companies, including Ore Pharmaceuticals, Biovista, Numedicus, Melior Discovery and SOM Biotech are also performing drug repositioning on a systematic basis. These companies use a combination of approaches including in silico biology and in vivo/in vitro experimentation to assess a compound and develop and confirm hypotheses concerning its usage for new indications.

  • Drug combinations
  • Drug action
  • Oncovaccines
  • Traditinal Vaccines
  • Clinical Trials
  • Pharmacotherapy

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