Case Reports in Oncology

Case report of Tumour heterogeneity are related in differences between tumours of the same type in different patients, and also difference between cancer cells within a tumour cells can show distinct  including cellular morphology, motility, gene expression, proliferation, metabolism, and metastatic potential. This process occurs both between tumours which is called as inter-tumour heterogeneity and within tumours called as intra-tumour heterogeneity. It plays a major role in brain Cancer.

Genetic and epigenetic differences between cancer cells within a tumour might explain why some tumour cells remain present in the patient even after cancer treatment has finished. Most current efforts are focused on understanding heterotypic interactions between tumor cells and surrounding normal cells, which is known about the interactions between and among heterogeneous tumor cells within a neoplasm. Tumor Heterogeneity covers Inter- intra tumour heterogeneity, Cancer Stem Cells, Brain Tumor Microenvironment, Experimental- Sequencing, Genetic Heterogeneity and Implications and challenges

Tumour heterogeneity describes the observation that different tumour cells can show distinct morphological and phenotypic profiles, including cellular morphology, gene expression, metabolism, motility, proliferation, and metastatic potential. This phenomenon occurs both between tumours (inter-tumour heterogeneity) and within tumours (intra-tumour heterogeneity). The heterogeneity of cancer cells introduces significant challenges in designing effective treatment strategies. However, research into understanding and characterizing heterogeneity can allow for a better understanding of the causes and progression of disease. In turn, this has the potential to guide the creation of more refined treatment strategies that incorporate knowledge of heterogeneity to yield higher efficacy

  • Cancer cell biology
  • Clinical trials in cencer biology
  • Clinical trial design in Neuroscience
  • Clinical Oncology
  • Role of immunotherapy in GSCs
  • Antitumor Activity

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