Cell signaling

Cell signalling is the natural biological process by which stimuli are transmitted via a signalling cascade to target molecules that leading to the desired response followed by a desensitization mechanism that allows cells to return to baseline. Cell signaling requires receptor molecule which is made up of Glycoproteins or Glycolipids located on cell surface to detect the signals. Numerous type of signalling pathways such as nutrient signalling, insulin signalling, stress signaling, Hippo signaling, TOR signaling and morphogen signaling are used by cells which altered protein confirmation to achieve a desired response. These cell signalling pathways are interconnected and affect each other. Techniques for the study of intracellular ions are used widely in living system, including for the tracking of calcium ions affecting cytosolic ph. To detect the changes in intracellular ion concentrations over time is essential for our understanding of signaling and functional pathways in biological system. Scientists and researchers have few good methods for investigating and manipulating G-protein signaling. Researchers have identified small peptides that selectively inhibit a certain type of G-protein signaling, have the advantages to develop potential drugs for various diseases involving abnormal G-protein signaling.

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