Childhood Obesity at Gene Level

Obesity tracks in families, and one of the strongest predictors of child overweight is the BMI of the mother and father. In recent years, progress was made in identifying genes that may contribute to this effect. The FTO (fat mass and obesity-associated) gene is a large gene on chromosome 16. The absolute risk generated by the FTO gene is relatively modest, is found in Caucasian populations, and is modifiable by environmental factors. 

The Human Obesity Gene Map summarizes the present situation in the field of common polygenic obesity. The genes include members of the leptin–melanocortin pathway, proinflammatory cytokines and uncoupling proteins. The largest numbers of studies have been carried out on ADRB2 (β2 adrenoreceptor) and PPARG (Peroxisome Proliferator-Activated Receptor Gamma) a Protein Coding gene, but the fact that they also have reported associations with asthma and Type 2 Diabetes, respectively.

  • The Genetics of Obesity
  • Nutrigenomics and Beyond
  • Risk of Obesity Among Siblings
  • Gene Therapy and Childhood Obesity
  • Candidate Gene Identification Approach
  • Association of Childhood Obesity with FTO
  • Twin Studies to Candidate Genes & Beyond
  • Gene Interactions Mastering Childhood Obesity
  • Implications of Epigenetics in Diabesity Syndrome
  • Alterations in Cytokine and Gene Expressions in Obesity
  • Role of Genotypic & Phenotypic Markers in Obesity

Related Conference of Childhood Obesity at Gene Level

Childhood Obesity at Gene Level Conference Speakers