Clinical Applications and Related Disorders

There are many Clinical Application and Related Disorders with Transcriptomics. Clinical Transcriptomics focus on the understanding of the molecular basis of diseases through translational research. The key aspects include genome-wide gene expression analysis from human patient samples. These techniques can be used to detect transcriptome involved in Neurological Disorders employing technologies such as RNA-Seq, Cap Analysis of Gene Expression (CAGE) or small RNA sequencing. Neurological disorders like Huntington disease involves a DNA segment known as a CAG Repeats. It’s a tri-nucleotide repeats that appear multiple times in a row. A very novel technique called INsPeCT (INtegrative Platform for Cancer Transcriptomics), which allows users with basic computer skills to perform comprehensive in-silico analyses of microarray, ChIP-seq, and RNA-seq data. Transcriptomics has a growing research in its clinical applications with major schools taking up it is a course like Karoliska Institutet, University of Bristol, University of Ferrara, Boston University School of Medicine and also being a part of major labs like SciLife Lab.

  • Clinical Transcriptomics
  • Neurological Disorders
  • CAG Repeats
  • INsPecT: Integrative Platform for Cancer Transcriptome
  • Applications

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