CNS Drug Discovery

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord. The central nervous system is so named because it integrates information it receives from, and coordinates and influences the activity of, all parts of the bodies of bilaterally symmetric animals — that is, all multicellular animals except sponges and radially symmetric animals such as jellyfish — and it contains the majority of the nervous system.

The universal market for treatments for central nervous system (CNS) disorders was valued at around US dollars 15 billion in 2011, and is set to raise sharply in the years ahead. This is because of a patent increase in the number of persons aged over 65 (the "baby boomer" effect), which will lead to increased demand for more safe and effective medicines for CNS disorders. 1) how to identify and confirm objects for potential CNS drugs; 2) how to assess brain penetration (both in vitro and in vivo); 3) how to develop in silico methodologies to predict blood-brain barrier dispersion; 4) how to estimate therapeutic efficacy (both in vitro and in vivo); 5) how to establish reliable biomarkers to guide decision making; and 6) how to efficiently apply magnetic resonance imaging to CNS drug discovery

  • Recent Patents on CNS Drug Discovery
  • Neuro imaging In CNS Drug Discovery
  • Neurodegenerative Diseases

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