Comparative Genomic Hybridization

\r\n Comparative genomic hybridization (CGH) is a molecular cytogenetic strategy for the identification and mapping of chromosomal gains and losses.  It depends on the cohybridization of differentially labeled test and reference DNAs onto metaphase spreads, which usually have been prepared from peripheral blood lymphocytes of a healthy donor. The signal intensity ratios of the two labels along the chromosomes then reflect DNA copy number changes in the test genome comparative with the reference genome.

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\r\n Comparative Genomic Hybridization

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\r\n Comparative genomic hybridization (CGH) is a molecular cytogenetic strategy for the identification and mapping of chromosomal gains and losses.  It depends on the cohybridization of differentially labeled test and reference DNAs onto metaphase spreads, which usually have been prepared from peripheral blood lymphocytes of a healthy donor. The signal intensity ratios of the two labels along the chromosomes then reflect DNA copy number changes in the test genome comparative with the reference genome.

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\r\n Microbial Genomics

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\r\n Microbial Genomics is a field of science that analyzes and compares the complete genome (genetic material of an organism) of a microorganisms or an enormous number of genes in a simultaneous manner. Microbial genomes are widely variable and reflect the enormous diversity of bacteria, archaea and lower eukaryotes. Bacterial genomes usually comprise of a single circular chromosome, but species with more than one chromosome (eg. Deinococcus radiodurans), linear chromosomes (eg. some Bacillis subtilis strains) and combinations of linear and circular chromosomes (eg. Agrobacterium tumefaciens) also exist.

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\r\n Human Genetics and Genomics

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\r\n Human genetics is the study of the inheritance of characteristics by children from parents. Inheritance in humans doesn't vary in any fundamental way from that in other organisms. The human genome is the finished arrangement of nucleic corrosive successions for individuals, encoded as DNA inside the 23 chromosome combines in cell cores and in a little DNA particle found inside individual mitochondria. These are typically treated independently as the atomic genome, and the mitochondrial genome.

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\r\n Gene Therapy and Genetic Counseling

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\r\n Gene therapy is a preliminary strategy that uses qualities or essentially nucleic corrosive polymers to treat or forestall malady into a patient's cell as a medication for illness treatment. Later on, this technique may enable specialists to treat confusion by embedding’s a quality into a patient's cells as opposed to using drugs or medical procedure. Gene Therapy is a way to settle a hereditary issue at its center or source. The polymers are either converted into proteins which meddle with the objective quality articulation or else they could rectify hereditary changes. Genetic counseling is the methodology by which an individual or people in danger of any acquired issue are informed and made mindful with respect to the results and nature of the confusion, and the likelihood of creating or transmitting it.

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\r\n Proteomics and Metagenomics

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\r\n Proteomics relates to the comprehensive analysis of expressed proteins from a cell, a multicellular system, an extracellular environment, or a large set of recombinant clones. This is accomplished utilizing combinations of protein separation, identification, and/or assay techniques, such as liquid chromatography-mass spectrometry (LC-MS), two-dimensional gel electrophoresis-mass spectrometry (2DE-MS), affinity purification-mass spectrometry (AP-MS), and protein- or antibody-based microarrays. Metagenomics is the process by which the metagenome is generated: it includes sequencing all DNA extracted from a sample followed by assembly of sequence reads or mapping them to a reference database followed by annotation of the genes.

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