Contribution of Microbiology to Pharmaceutical Industries

 The most important contribution of microbiology to the pharmaceutical the development of antibiotics. All antibiotics were originally the products of microbial metabolism; The recent genetic manipulations have enabled the production of more enhanced drugs. Vaccines are also a very important contribution of microbiology towards development of drugs. The production of vaccines against bacterial diseases usually requires the growth of large amounts of bacteria. Steroids can also be obtained from microorganisms. Apart from drugs and bio products development, microbiology contributes towards quality control of a pharmaceutical laboratory. Prevention of microbial contamination of drugs, injectable, eye drops, nasal solutions and inhalation products is undertaken following the pharmacopeial guidelines. Growth promotion tests establish the potential of any media to support growth when the inoculum contains a small number of microorganisms. Microbial limit testing and sterility testing are used to identify the microbial load of the product.. Bioburden is the total number of microorganisms present on a product prior to sterilisation. Water is one of the major commodities consumed by the pharmaceutical industry. Total viable count is studied to rule out microbial contamination. 

  • Growth Promotion Test
  • Sterility testing
  • Microbial Limits Test
  • Bioburden Testing
  • Water Testing
  • Bacterial Endotoxing Test
  • Applications of microbial techniques in the synthesis of pharmaceuticals
  • Microorganisms and their Byproducts
  • Microorganisms as models in Drug metabolism

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