Controlled & Sustained Release Drug Delivery

Controlled drug delivery is that type of system which release the medicaments from the dosage form at a predetermined specified rate for locally or systemically for a specified period of time. The main advantages of controlled drug delivery are – 1. Low amount of administered doses; 2. Less gastrointestinal side effects; 3. Less dosing frequency; 4. Improved patient acceptance & compliance; 5. Less ups & downs in plasma drug concentration; 6. Highly uniform drug action & effect; 7. Enhanced efficacy & drug safety.

The sustained release formulation is those which give slow but prolonged action. I.e. giving action for a long period of action without hampering the drug concentration.  Sustained release formulation maintains uniform drug plasma concentration. But the all type of medicaments cannot be administered through the sustained release drug delivery. Enteric coated tablet and capsule, implantable tablet are the example of this type of system. Reservoir type of mechanism is associated with this type of system.

  • Prolonged action
  • Enhancement of half-life of drug
  • Slow action
  • Poor dissolution rate
  • Site specific action
  • Enteric coated materials & Tablet hardness
  • Natural & Synthetic polymer

Related Conference of Controlled & Sustained Release Drug Delivery

Controlled & Sustained Release Drug Delivery Conference Speakers