Diagnosis in Dermatopathology

Among the classic diagnostic investigations are the use of Wood's light in many dermatologic disorders eg, vitiligo, pityriasis versicolor, erythrasma, porphyrias, cytodiagnosis of Tzanck in dermatologic practice eg, herpetic infections, molluscum contagiosum, leishmaniasis, pemphigus vulgaris, basal cell carcinoma, erythroplasia of Queyrat, Hailey-Hailey disease and microscopic examination for fungal and bacterial skin infections as well as for mite infestation using potassium hydroxide, simple saline, and Gram stain. Modern molecular biotechnologies encompassing gene-specific polymerase chain reaction and its variants have a substantial affect in selected cases of viral especially herpes simplex virus, bacterial, fungal, and protozoan Leishmania skin infections.

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