Diagnosis, Management and Treatment of Infectious

The most important causes of sepsis are pneumonias, followed by intra-abdominal and urinary tract infections actually, the high use of endovascular prosthesis and devices represent an important risk factor of infection and its complications. Bacteria are the most common cause of sepsis, both Gram-positive and Gram-negative. Staphylococcus aureus and Streptococcus pneumoniae are the most common Gram-positive isolates, while Escherichia Coli, Klebsiella spp., and Pseudomonas aeruginosa are the most represented among Gram-negative isolates.

There is an increasing role of methicillin- resistant Staphylococcus aureus (MRSA), not only in hospitalized patients, but also in community acquired infections. Until 2016, sepsis was defined as a “Systemic inflammatory response syndrome (SIRS) with a documented infection” while severe sepsis was defined as “A systemic inflammatory response syndrome with a documented infection, related to organ failure, hypotension or reduced tissue function

  • Laboratory tests
  • Biopsies
  • Antivirals
  • Anti-parasitics

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